Monomicrobial necrotizing fasciitis in a white male caused by hypermucoviscous Klebsiella pneumoniae

Gudjon L Gunnarsson; Pernille B Brandt; Dorte Gad; Carsten Struve; Ulrik S Justesen

doi:10.1099/jmm.0.011064-0

Monomicrobial necrotizing fasciitis in a white male caused by hypermucoviscous Klebsiella pneumoniae

J Med Microbiol. 2009 Nov;58(Pt 11):1519-1521. doi: 10.1099/jmm.0.011064-0. Epub 2009 Aug 6.

Authors

Gudjon L Gunnarsson¹, Pernille B Brandt², Dorte Gad¹, Carsten Struve³, Ulrik S Justesen²

Affiliations

¹ Department of Plastic Surgery, Odense University Hospital, Odense, Denmark.
² Department of Clinical Microbiology, Odense University Hospital, Odense, Denmark.
³ Department of Bacteriology, Mycology and Parasitology, Statens Serum Institut, Copenhagen, Denmark.

PMID: 19661201
DOI: 10.1099/jmm.0.011064-0

Abstract

We report a case of monomicrobial necrotizing fasciitis caused by hypermucoviscous Klebsiella pneumoniae in an immunocompromised white male after travel to China. The K. pneumoniae isolate belonged to the K2 serotype, and carried the virulence factors RmpA and aerobactin. To the best of our knowledge this is the first report of necrotizing fasciitis caused by hypermucoviscous K. pneumoniae resembling the highly virulent K. pneumoniae isolates associated with liver abscess syndrome in Asia.

Publication types

Case Reports

MeSH terms

Aged
Bacterial Proteins / genetics
Denmark
Fasciitis, Necrotizing / microbiology*
Fasciitis, Necrotizing / physiopathology
Humans
Hydroxamic Acids / metabolism
Klebsiella Infections / microbiology*
Klebsiella Infections / physiopathology
Klebsiella pneumoniae / classification
Klebsiella pneumoniae / genetics
Klebsiella pneumoniae / isolation & purification*
Klebsiella pneumoniae / pathogenicity
Male
Polymerase Chain Reaction / methods
Serotyping

Substances

Bacterial Proteins
Hydroxamic Acids
RmpA protein, Klebsiella pneumoniae
aerobactin