Residue analysis of kresoxim-methyl and boscalid in fruits, vegetables and soil using liquid-liquid extraction and gas chromatography-mass spectrometry

Biomed Chromatogr. 2010 Apr;24(4):367-73. doi: 10.1002/bmc.1301.

Abstract

A GC-MS procedure for simultaneously determining and validating kresoxim-methyl and boscalid has been developed in fruit, vegetable and soil matrices. The method was based on one-step liquid-liquid extraction with acetone and dichloromethane solvents. Estimated limits of detection (LODs) for kresoxim-methyl and boscalid were 0.006 and 0.015 mg/kg, and limits of quantification (LOQs) were 0.02 and 0.05 mg/kg, respectively. The intra- and inter- precision were achieved with RSD better than 13.8 and 14.5%, and recoveries were in the range of 77.1-98.7% for kresoxim-methyl and 72.8-105.1% for boscalid. The expanded uncertainties calculated at 0.1 mg/kg were below 18%. Concentration levels for residues of the two fungicides in melon samples from field trials collected 7 days after the last application were clearly below the established MRL values.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biphenyl Compounds / analysis
  • Biphenyl Compounds / chemistry
  • Chemical Fractionation / methods*
  • Fruit / chemistry*
  • Fungicides, Industrial / analysis
  • Fungicides, Industrial / chemistry
  • Gas Chromatography-Mass Spectrometry / methods*
  • Methacrylates / analysis
  • Methacrylates / chemistry
  • Niacinamide / analogs & derivatives*
  • Niacinamide / analysis
  • Niacinamide / chemistry
  • Phenylacetates / analysis*
  • Phenylacetates / chemistry
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Soil / analysis*
  • Soil Pollutants / analysis
  • Soil Pollutants / chemistry
  • Strobilurins
  • Vegetables / chemistry*

Substances

  • Biphenyl Compounds
  • Fungicides, Industrial
  • Methacrylates
  • Phenylacetates
  • Soil
  • Soil Pollutants
  • Strobilurins
  • kresoxim-methyl
  • Niacinamide
  • 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide