Evaluation of ceftiofur and cefquinome for phenotypic detection of methicillin resistance in Staphylococcus aureus using disk diffusion testing and MIC-determinations

Frank M Aarestrup; Robert L Skov

doi:10.1016/j.vetmic.2009.07.005

Evaluation of ceftiofur and cefquinome for phenotypic detection of methicillin resistance in Staphylococcus aureus using disk diffusion testing and MIC-determinations

Vet Microbiol. 2010 Jan 6;140(1-2):176-9. doi: 10.1016/j.vetmic.2009.07.005. Epub 2009 Jul 10.

Authors

Frank M Aarestrup¹, Robert L Skov

Affiliation

¹ Community Reference Laboratory for Antimicrobial Resistance and WHO Collaborating Centre for Antimicrobial Resistance in Foodborne Pathogens, National Food Institute, Technical University of Denmark, Bülowsvej 27, DK-1790 Copenhagen V, Denmark. fmaa@food.dtu.dk

PMID: 19643555
DOI: 10.1016/j.vetmic.2009.07.005

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) have emerged in animals. Testing 98 mecA negative and 71 mecA positive S. aureus we compared the usefulness of ceftiofur and cefquinome to cefoxitin, for detection of MRSA and found that these cephalosporins are not as efficient as cefoxitin.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Anti-Bacterial Agents / pharmacology*
Cephalosporins / pharmacology*
Disk Diffusion Antimicrobial Tests / methods*
Humans
Methicillin-Resistant Staphylococcus aureus / classification*
Methicillin-Resistant Staphylococcus aureus / drug effects*
Microbial Sensitivity Tests / methods
Phenotype
Sensitivity and Specificity
Staphylococcal Infections / microbiology*
Swine
Swine Diseases / microbiology

Substances

Anti-Bacterial Agents
Cephalosporins
ceftiofur
cefquinome