Comparison of the clinical value of CA 19-9 versus CA 125 for the diagnosis of endometriosis

Fertil Steril. 2009 Nov;92(5):1761-3. doi: 10.1016/j.fertnstert.2009.05.022. Epub 2009 Jul 23.

Abstract

Preoperative blood samples and intraoperative tissue specimens were obtained from 101 patients with endometriosis and 78 patients without endometriosis referred for benign gynecologic operations to investigate the clinical value of serum and tissue CA 19-9 levels in the diagnostic evaluation of endometriosis as compared to CA 125. Our prospective cohort study showed that serum CA 19-9 is a valuable marker in the diagnosis of endometriosis, and it may be used to predict the patients with severe endometriosis when used with CA 125.

Publication types

  • Comparative Study
  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomarkers / analysis
  • Biomarkers / blood
  • Biomarkers / metabolism
  • Biopsy
  • CA-125 Antigen / analysis
  • CA-125 Antigen / blood*
  • CA-125 Antigen / metabolism
  • CA-19-9 Antigen / analysis
  • CA-19-9 Antigen / blood*
  • CA-19-9 Antigen / metabolism
  • Case-Control Studies
  • Endometriosis / blood
  • Endometriosis / diagnosis*
  • Endometriosis / metabolism
  • Endometriosis / pathology
  • Female
  • Humans
  • Intraoperative Period
  • Ovarian Diseases / blood
  • Ovarian Diseases / diagnosis*
  • Ovarian Diseases / metabolism
  • Ovarian Diseases / pathology
  • Predictive Value of Tests
  • Reference Values
  • Sensitivity and Specificity

Substances

  • Biomarkers
  • CA-125 Antigen
  • CA-19-9 Antigen