Unnatural rigid scaffolds targeting the bacterial ribosome

Chembiochem. 2009 Aug 17;10(12):1969-72. doi: 10.1002/cbic.200900268.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aminoglycosides / chemical synthesis
  • Aminoglycosides / chemistry
  • Aminoglycosides / pharmacology*
  • Anti-Bacterial Agents / chemical synthesis
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology*
  • Binding Sites
  • Crystallography, X-Ray
  • Drug Design
  • Escherichia coli / chemistry*
  • Escherichia coli / drug effects
  • Models, Molecular
  • Molecular Conformation
  • Molecular Weight
  • RNA, Ribosomal / chemistry
  • RNA, Ribosomal / drug effects*
  • RNA, Ribosomal / genetics
  • Ribosomes / chemistry
  • Ribosomes / drug effects*
  • Ribosomes / genetics
  • Stereoisomerism

Substances

  • Aminoglycosides
  • Anti-Bacterial Agents
  • RNA, Ribosomal