Multicomponent exercise program improves blood lipid profile and antioxidant capacity in older women

Arch Gerontol Geriatr. 2010 Jul-Aug;51(1):1-5. doi: 10.1016/j.archger.2009.05.020. Epub 2009 Jul 3.

Abstract

This study intended to determine the effect of multicomponent exercise on blood lipid profile and on antioxidant capacity in older women. Forty women aged 60-80 years participated in a supervised multicomponent exercise program. Plasma contents of total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), apolipoprotein A-1 (Apo A-1) and apolipoprotein B (Apo B-100), total antioxidant status (TAS) and the enzymatic activities of glutathione reductase (GR) and glutathione peroxidase (GPx) were evaluated before and after 8-month training. The multicomponent exercise program induced a significant decrease in TG, TC/HDL-C and Apo B/Apo A-1 and a significant increase in HDL-C and Apo A-1 (p<0.05). There was a significant increase in plasma TAS as well as GR and GPx enzyme activities. The present data show that an 8-month supervised moderate-intensity multicomponent exercise program resulted in beneficial improvements of blood lipid profile that were accompanied by positive modulation of antioxidant capacity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Antioxidants / metabolism*
  • Apolipoprotein A-I / blood*
  • Apolipoprotein B-100 / blood
  • Cholesterol, LDL / blood*
  • Exercise*
  • Female
  • Glutathione Reductase / metabolism
  • Health Promotion*
  • Humans
  • Hyperlipidemias / blood*
  • Hyperlipidemias / prevention & control*
  • Program Development*
  • Triglycerides / metabolism

Substances

  • Antioxidants
  • Apolipoprotein A-I
  • Apolipoprotein B-100
  • Cholesterol, LDL
  • Triglycerides
  • Glutathione Reductase