Abstract
We identified 1,805 gram-negative organisms in cultures of urine samples obtained over a 10-month period from residents of 63 long-term care facilities. The prevalence of fluoroquinolone resistance in Escherichia coli was 51% (446 of 874 isolates), whereas the prevalences of ceftazidime and imipenem resistance in Klebsiella species were 26% and 6% (84 and 19 of 323 isolates), respectively. The prevalence of resistance varied significantly by facility type, size, and geographic location.
Publication types
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Multicenter Study
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Anti-Bacterial Agents / therapeutic use
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Ceftazidime / therapeutic use
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Colony Count, Microbial
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Cross Infection / drug therapy
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Cross Infection / epidemiology*
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Cross Infection / microbiology
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Cross Infection / urine
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Cross-Sectional Studies
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Delaware / epidemiology
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Drug Resistance, Bacterial*
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Escherichia coli / drug effects
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Escherichia coli / isolation & purification
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Fluoroquinolones / therapeutic use
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Gram-Negative Bacterial Infections / drug therapy
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Gram-Negative Bacterial Infections / epidemiology*
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Gram-Negative Bacterial Infections / microbiology
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Gram-Negative Bacterial Infections / urine
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Humans
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Imipenem / therapeutic use
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Klebsiella / drug effects
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Klebsiella / isolation & purification
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Long-Term Care / statistics & numerical data
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Microbial Sensitivity Tests
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New Jersey / epidemiology
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Pennsylvania / epidemiology
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Prevalence
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Proteus mirabilis / drug effects
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Proteus mirabilis / isolation & purification
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Skilled Nursing Facilities / statistics & numerical data*
Substances
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Anti-Bacterial Agents
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Fluoroquinolones
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Imipenem
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Ceftazidime