Mid-term outcomes in adults with ebstein anomaly and cavopulmonary shunts

Ann Thorac Surg. 2009 Jul;88(1):131-6. doi: 10.1016/j.athoracsur.2009.03.062.

Abstract

Background: In patients with Ebstein anomaly and poorly functioning right ventricles, a cavopulmonary shunt (CPS) can be created to reduce the preload on the right ventricle. The purpose of this study was to examine the early and mid-term outcomes in adults with Ebstein anomaly who have undergone tricuspid valve repair or replacement with or without a concomitant CPS.

Methods: We examined the outcomes of 40 consecutive patients seen at our center with Ebstein anomaly who had undergone tricuspid valve repair or replacement with (n = 23) or without (n = 17) concomitant CPS. Follow-up data were obtained by either chart review or contacting the referring cardiologist. Mid-term survival was examined using Kaplan-Meier curves.

Results: The mean age at surgery was similar in patients with and without CPS (42 +/- 12 versus 39 +/- 19 years; p = 0.63). There were 2 early postoperative deaths owing to refractory right-sided heart failure. Mid-term follow-up data were available in 95% of patients. The mean follow-up time was 6.7 +/- 4.8 years. Patients who received a CPS more commonly had preoperative heart failure or cyanosis (p = 0.04) and had worse preoperative functional status (p = 0.09). In both groups, arrhythmias were the most common late complication. There were 5 late deaths, 3 of which occurred in patients with CPS. Five-year survival with or without CPS was comparable (83% +/- 9% versus 86% +/- 10%; p = 0.85).

Conclusions: Adolescent and adult patients with Ebstein anomaly undergoing tricuspid valve replacement or repair and concomitant CPS are at risk for early and mid-term complications. However, Ebstein surgery along with CPS appears to be a reasonable surgical strategy in patients not thought to be suitable for tricuspid valve surgery alone.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Cardiac Surgical Procedures / adverse effects
  • Cardiac Surgical Procedures / methods*
  • Cohort Studies
  • Ebstein Anomaly / diagnosis
  • Ebstein Anomaly / mortality
  • Ebstein Anomaly / surgery*
  • Education, Medical, Continuing
  • Female
  • Follow-Up Studies
  • Heart Bypass, Right / methods*
  • Heart Valve Prosthesis Implantation / methods
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Probability
  • Risk Assessment
  • Statistics, Nonparametric
  • Survival Analysis
  • Time Factors
  • Treatment Outcome
  • Tricuspid Valve / surgery*
  • Ventricular Dysfunction, Right / diagnosis
  • Ventricular Dysfunction, Right / mortality
  • Ventricular Dysfunction, Right / surgery*
  • Young Adult