Reversible cardiogenic shock following 5-fluorouracil infusion

Invest New Drugs. 2010 Aug;28(4):531-3. doi: 10.1007/s10637-009-9271-3. Epub 2009 Jun 5.

Abstract

5-Fluorouracil remains a major component of chemotherapy regimens for various tumors. We report the case of reversible cardiogenic shock following 5-FU administration and discuss the different pitfalls of such toxicity. Oncologist should be aware of that rare but potentially lethal adverse event.

Publication types

  • Case Reports

MeSH terms

  • Antimetabolites, Antineoplastic / administration & dosage
  • Antimetabolites, Antineoplastic / adverse effects*
  • Fluorouracil / administration & dosage
  • Fluorouracil / adverse effects*
  • Humans
  • Infusions, Intravenous
  • Male
  • Middle Aged
  • Shock, Cardiogenic / chemically induced*

Substances

  • Antimetabolites, Antineoplastic
  • Fluorouracil