Glucuronidation of morphine and some drug oxidation reactions in liver microsomes from pregnant and non-pregnant rhesus monkeys

Pharmacol Toxicol. 1991 Jul;69(1):78-80. doi: 10.1111/j.1600-0773.1991.tb00415.x.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 7-Alkoxycoumarin O-Dealkylase / metabolism
  • Animals
  • Cytochrome P-450 CYP1A1
  • Cytochrome P-450 Enzyme System / metabolism
  • Ethylmorphine-N-Demethylase / metabolism
  • Female
  • Glucuronates / metabolism
  • Glucuronosyltransferase / metabolism
  • Immunoblotting
  • Kinetics
  • Macaca mulatta
  • Microsomes, Liver / metabolism*
  • Morphine / metabolism*
  • Morphine Derivatives / metabolism
  • Oxidation-Reduction
  • Oxidoreductases / metabolism
  • Pharmaceutical Preparations / metabolism*
  • Pregnancy
  • Pregnancy, Animal / metabolism*
  • Proteins / metabolism

Substances

  • Glucuronates
  • Morphine Derivatives
  • Pharmaceutical Preparations
  • Proteins
  • Morphine
  • Cytochrome P-450 Enzyme System
  • Oxidoreductases
  • 7-Alkoxycoumarin O-Dealkylase
  • Cytochrome P-450 CYP1A1
  • Ethylmorphine-N-Demethylase
  • Glucuronosyltransferase
  • morphine-3-glucuronide