A balancing act: efflux/influx in mycobacterial drug resistance

Antimicrob Agents Chemother. 2009 Aug;53(8):3181-9. doi: 10.1128/AAC.01577-08. Epub 2009 May 18.

Authors

G E Louw¹, R M Warren, N C Gey van Pittius, C R E McEvoy, P D Van Helden, T C Victor

Affiliation

¹ DST/NRF Centre of Excellence in Biomedical Tuberculosis Research/MRC Centre for Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Stellenbosch University, Tygerberg 7505, South Africa.

No abstract available

Publication types

Review

MeSH terms

Antitubercular Agents / pharmacology
Bacterial Proteins / genetics
Bacterial Proteins / metabolism
Bacterial Proteins / physiology
Biological Transport / physiology*
Drug Resistance, Multiple, Bacterial / genetics
Drug Resistance, Multiple, Bacterial / physiology*
Membrane Transport Proteins / genetics
Membrane Transport Proteins / metabolism
Membrane Transport Proteins / physiology
Mycobacterium / drug effects
Mycobacterium / metabolism*

Substances

Antitubercular Agents
Bacterial Proteins
Membrane Transport Proteins