Jaundice revealing a k light chain myeloma because of liver light chain deposits

Eur J Gastroenterol Hepatol. 2009 Jul;21(7):827-9. doi: 10.1097/MEG.0b013e3282ff0f6f.

Abstract

We report the case of a 77-year-old man referred for jaundice and diagnosed with intrahepatic light chain deposit as primary manifestation of a kappa light chain multiple myeloma. Jaundice is a very rare way of presentation for myeloma. In our observation, diagnosis was made by liver biopsy, which found light chain deposits infiltrating perisinusoidal spaces. We discuss jaundice's possible mechanisms in myeloma.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Fatal Outcome
  • Humans
  • Immunoglobulin kappa-Chains / analysis*
  • Jaundice / etiology*
  • Jaundice / pathology
  • Liver / immunology*
  • Liver / pathology
  • Liver Diseases / etiology*
  • Liver Diseases / immunology
  • Liver Diseases / pathology
  • Male
  • Multiple Myeloma / complications*
  • Multiple Myeloma / pathology

Substances

  • Immunoglobulin kappa-Chains