Abstract
Two unusual trinorsesquiterpenoids, urechitols A (1) and B (2), were isolated from the root extract of Pentalinon andrieuxii, a plant used commonly in Yucatecan traditional medicine to treat leishmaniasis. The structures of 1 and 2 were identified by interpretation of their spectroscopic data and chemical correlation reactions. The relative stereochemistry of 1 was confirmed through an X-ray crystallographic study.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Apocynaceae / chemistry*
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Crystallography, X-Ray
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Leishmaniasis / drug therapy*
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Medicine, Traditional
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Mexico
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Molecular Conformation
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Molecular Structure
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Phytotherapy
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Plant Roots / chemistry
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Plants, Medicinal / chemistry*
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Sesquiterpenes / chemistry
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Sesquiterpenes / isolation & purification*
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Sesquiterpenes / pharmacology
Substances
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Sesquiterpenes
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urechitol A
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urechitol B