This study investigated the effect of 'Alpron mint', a dental unit waterline disinfectant, on shear bond strengths between 'Panavia 21' resin based cement and tooth tissue. Eighty-eight human premolar tooth specimens were prepared in either enamel (N=44) or dentine (N=44). Half the specimens within each group were irrigated with an Alpron mint solution and the other half with distilled water (control) prior to application of Panavia 21 resin luting cement. There was no significant difference in shear bond strengths for both enamel and dentine with Alpron mint irrigation compared with distilled water (P = 0.245).