Application of Lifeact reveals F-actin dynamics in Arabidopsis thaliana and the liverwort, Marchantia polymorpha

Plant Cell Physiol. 2009 Jun;50(6):1041-8. doi: 10.1093/pcp/pcp055. Epub 2009 Apr 15.

Abstract

Actin plays fundamental roles in a wide array of plant functions, including cell division, cytoplasmic streaming, cell morphogenesis and organelle motility. Imaging the actin cytoskeleton in living cells is a powerful methodology for studying these important phenomena. Several useful probes for live imaging of filamentous actin (F-actin) have been developed, but new versatile probes are still needed. Here, we report the application of a new probe called Lifeact for visualizing F-actin in plant cells. Lifeact is a short peptide comprising 17 amino acids that was derived from yeast Abp140p. We used a Lifeact-Venus fusion protein for staining F-actin in Arabidopsis thaliana and were able to observe dynamic rearrangements of the actin meshwork in root hair cells. We also used Lifeact-Venus to visualize the actin cytoskeleton in the liverwort Marchantia polymorpha; this revealed unique and dynamic F-actin motility in liverwort cells. Our results suggest that Lifeact could be a useful tool for studying the actin cytoskeleton in a wide range of plant lineages.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Actins / metabolism*
  • Arabidopsis / cytology*
  • Arabidopsis / genetics
  • Bacterial Proteins / metabolism
  • Luminescent Proteins / metabolism
  • Marchantia / cytology*
  • Marchantia / genetics
  • Microscopy, Fluorescence
  • Molecular Probes / metabolism*
  • Peptides / metabolism
  • Plants, Genetically Modified / cytology
  • Plants, Genetically Modified / genetics
  • Staining and Labeling / methods

Substances

  • Actins
  • Bacterial Proteins
  • Luminescent Proteins
  • Molecular Probes
  • Peptides
  • yellow fluorescent protein, Bacteria