Poly(para-dioxanone)/inorganic particle composites as a novel biomaterial

J Biomed Mater Res B Appl Biomater. 2009 Aug;90(2):945-51. doi: 10.1002/jbm.b.31367.

Abstract

In this work, poly(para-dioxanone) (PPDO) was mixed with 1% (by weight) calcium carbonate (CaCO(3)), beta-tricalcium phosphate (beta-TCP), or calcium sulphate dihydrate (CSD) by solution co-precipitation. Samples were compression molded into bars using a platen-vulcanizing press. The morphology, thermal and mechanical properties, and crystalline structure of the composites were investigated using differential scanning calorimetry, polarized optical microscopy, scanning electron microscopy, and X-ray diffraction. All results suggest that three types of inorganic particle in this system promote the crystallinity of PPDO and act as an effective nucleating agent: the relative degree of crystallinity of PPDO increased from 30.74% to 100%, and the crystallization temperature of PPDO was increased by 18 degrees C. On the other hand, the mechanical properties of PPDO were changed by the presence of inorganic particles: the tensile strength of PPDO/CSD increased by 11.46%.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biocompatible Materials / chemistry*
  • Calcium Carbonate / chemistry*
  • Calcium Phosphates / chemistry*
  • Calcium Sulfate / chemistry*
  • Calorimetry, Differential Scanning / methods
  • Dioxanes / chemistry*
  • Inorganic Chemicals
  • Microscopy, Electron, Scanning / methods
  • Polymers / chemistry
  • Powders
  • Stress, Mechanical
  • Temperature
  • Tensile Strength
  • X-Ray Diffraction

Substances

  • Biocompatible Materials
  • Calcium Phosphates
  • Dioxanes
  • Inorganic Chemicals
  • Polymers
  • Powders
  • beta-tricalcium phosphate
  • Calcium Carbonate
  • 4-dioxanone
  • Calcium Sulfate