Abstract
Inflammation is a hallmark of various diseases like infections, autoimmune syndromes, cardiovascular and neurodegenerative disorders, and cancer. Thereby, Th1-type cytokine interferon-gamma is a central pro-inflammatory mediator. Antioxidant compounds counteract the activation of T-cells and macrophages. This anti-inflammatory activity could be important for the development of immunotolerance and for treatment of above-mentioned disorders.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Anti-Inflammatory Agents / pharmacology
-
Antioxidants / pharmacology*
-
Humans
-
Immune Tolerance / drug effects
-
Inflammation / drug therapy*
-
Inflammation / immunology
-
Interferon-gamma / immunology
-
Macrophages / drug effects
-
Macrophages / immunology
-
Plant Extracts / pharmacology
-
Th1 Cells / immunology*
Substances
-
Anti-Inflammatory Agents
-
Antioxidants
-
Plant Extracts
-
Interferon-gamma