Abstract
The Klebsiella pneumoniae carbapenemase (KPC) was detected in a carbapenem-resistant respiratory isolate of Klebsiella pneumoniae in an Irish hospital. This is the first report of a KPC-producing isolate in the Republic of Ireland. The isolate was resistant to all beta-lactams. Furthermore, it had reduced susceptibility to three other classes of non-beta-lactam antibiotics. The isolate was not associated with travel abroad. Detection of KPC-producing bacteria has important infection control and public health implications.
MeSH terms
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Bacterial Proteins / analysis*
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Bacterial Proteins / genetics
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Cross Infection / microbiology
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Drug Resistance, Multiple, Bacterial
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Humans
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Ireland / epidemiology
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Klebsiella Infections / drug therapy
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Klebsiella Infections / epidemiology*
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Klebsiella Infections / microbiology
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Klebsiella pneumoniae / enzymology*
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Klebsiella pneumoniae / isolation & purification
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Male
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Middle Aged
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Penicillanic Acid / analogs & derivatives
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Penicillanic Acid / therapeutic use
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Piperacillin / therapeutic use
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Pneumonia, Bacterial / drug therapy
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Pneumonia, Bacterial / epidemiology*
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Pneumonia, Bacterial / microbiology
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Tazobactam
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beta-Lactamases / analysis*
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beta-Lactamases / genetics
Substances
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Bacterial Proteins
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Penicillanic Acid
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beta-Lactamases
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carbapenemase-2, Klebsiella pneumoniae
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Tazobactam
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Piperacillin