Environmentally friendly sonocatalysis promoted preparation of 1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-1H-pyrazoles

Ultrason Sonochem. 2009 Aug;16(6):728-31. doi: 10.1016/j.ultsonch.2009.02.005. Epub 2009 Feb 25.

Abstract

An efficient and green synthesis of thiocarbamoyl-3,5-diaryl-4,5-dihydro-1H-pyrazoles via the condensation of chalcones with thiosemicarbazide in ethanol and KOH under ultrasound irradiation is reported. The products were isolated in good yields after short reaction times.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Ethanol / chemistry
  • Green Chemistry Technology / methods*
  • Pyrazoles / chemical synthesis*
  • Pyrazoles / chemistry
  • Solvents / chemistry
  • Sonication
  • Ultrasonics*

Substances

  • Pyrazoles
  • Solvents
  • Ethanol