Pleural mesothelioma: an unusual case diagnosed on pleural fluid cytology and immunocytochemistry

Diagn Cytopathol. 2009 Jul;37(7):509-12. doi: 10.1002/dc.21063.

Abstract

Mesothelioma is a rare neoplasm with relationship to occupational and environmental exposure to asbestos. Its accurate and early diagnosis is often difficult. We present an unusual clinical presentation and diagnostic dilemma in a 30-year-male, who presented with neck pain and diffuse edema of left upper limb. The color Doppler ultrasound revealed venous thrombosis. The right supraclavicular lymph node biopsy revealed a poorly differentiated carcinoma. The patient had mild bilateral pleural effusion, the characteristic cytomorphological features of mesothelioma on fluid cytology were helpful in establishing the diagnosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Humans
  • Immunohistochemistry
  • Male
  • Mesothelioma / diagnosis
  • Mesothelioma / diagnostic imaging
  • Mesothelioma / pathology*
  • Pleural Effusion, Malignant / diagnostic imaging
  • Pleural Effusion, Malignant / pathology*
  • Sentinel Lymph Node Biopsy
  • Ultrasonography, Doppler, Color
  • Venous Thrombosis / diagnostic imaging
  • Venous Thrombosis / pathology