Both a protective and a deleterious role for the L76V mutation

MeSH terms

• Acquired Immunodeficiency Syndrome / drug therapy*
• Acquired Immunodeficiency Syndrome / virology
• Anti-HIV Agents / therapeutic use*
• Darunavir
• Drug Resistance, Multiple, Viral / genetics*
• HIV Protease / genetics*
• HIV Protease Inhibitors / therapeutic use*
• HIV-1*
• Humans
• Lopinavir
• Mutation*
• Pyridines / therapeutic use
• Pyrimidinones / therapeutic use*
• Pyrones / therapeutic use
• Sulfonamides / pharmacology