Double dissociation between perspective-taking and empathic-concern as predictors of hemodynamic response to another's mistakes

Soc Cogn Affect Neurosci. 2009 Jun;4(2):111-8. doi: 10.1093/scan/nsn043. Epub 2009 Feb 25.

Abstract

Identifying another's mistakes requires a basic representation of other's action patterns as well as recognition and understanding of their failed goal-attainment. In previous work, we identified several regions, including inferior parietal cortex and rostral/ventral anterior cinguli (r/vACC), that show unique sensitivity to the observation of another's errors. Here we utilize the same sample to show that participants' level of self-reported perspective-taking (but not empathic concern) correlated with hemodynamic response in IPC, while participants' level of self-reported empathic concern (but not perspective taking) correlated with hemodynamic response in r/vACC. This functional dissociation provides strong evidence for separate roles for IPC and r/vACC in the processing of observed errors. IPC may foster a sense of agency by distinguishing self- from other-performed actions; r/vACC may, in turn, promote a more contextually-mediated understanding of the other's failed goal-attainment.

MeSH terms

  • Adolescent
  • Adult
  • Brain Mapping*
  • Decision Making / physiology*
  • Emotions / physiology*
  • Empathy*
  • Female
  • Humans
  • Image Processing, Computer-Assisted / methods
  • Intention*
  • Interpersonal Relations
  • Magnetic Resonance Imaging / methods
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Oxygen / blood
  • Parietal Lobe / blood supply*
  • Photic Stimulation
  • Young Adult

Substances

  • Oxygen