Abstract
Two naturally occurring compounds, curcumin, the active ingredient in the spice turmeric, and the green tea extract epigallocatechin-3-gallate, have marked effects on the apoptotic machinery in chronic lymphocytic leukemia. These results provide a preclinical foundation for future clinical use of these compounds in this disease.
Publication types
-
Comment
-
Research Support, N.I.H., Extramural
MeSH terms
-
Apoptosis / drug effects
-
Catechin / administration & dosage
-
Catechin / analogs & derivatives*
-
Catechin / pharmacology
-
Curcuma
-
Curcumin / administration & dosage
-
Curcumin / pharmacology*
-
Humans
-
Leukemia, Lymphocytic, Chronic, B-Cell / drug therapy*
-
Tea
Substances
-
Tea
-
Catechin
-
epigallocatechin gallate
-
Curcumin