Mastocytosis of the female breast

Int J Surg Pathol. 2010 Oct;18(5):374-8. doi: 10.1177/1066896909331998. Epub 2009 Feb 17.

Abstract

A subset of patients with systemic mastocytosis may manifest with extracutaneous involvement. To the best of our knowledge, mastocytosis of the human breast has not been described. This study reports a case with mastocytosis involving the breasts of a 33-year-old woman associated with mammary hypertrophy (breast mastocytosis). The potential for infiltrating mast cells to mimic lobular carcinoma is emphasized and the relationship to breast hypertrophy in this case is discussed.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Biomarkers / metabolism
  • Breast Diseases / metabolism
  • Breast Diseases / pathology*
  • Breast Diseases / surgery
  • Breast Neoplasms / diagnosis
  • Carcinoma, Lobular / diagnosis
  • Diagnosis, Differential
  • Female
  • Humans
  • Immunohistochemistry
  • Mammaplasty / methods
  • Mast Cells / metabolism
  • Mast Cells / pathology
  • Mastocytosis, Systemic / metabolism
  • Mastocytosis, Systemic / pathology*
  • Mastocytosis, Systemic / surgery
  • Middle Aged
  • Young Adult

Substances

  • Biomarkers