Abstract
Multidrug-resistant tuberculosis (TB) strains resistant to the fluoroquinolones and streptomycin but susceptible to second-line injection treatment would not be defined as extensively drug-resistant TB. In a cohort of 174 patients with multidrug-resistant TB, we demonstrated that 12 patients with multidrug-resistant TB strains resistant to the fluoroquinolones and streptomycin had significantly better initial and long-term outcomes, compared with 10 patients with extensively drug-resistant TB.
Publication types
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Comparative Study
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Antitubercular Agents / therapeutic use*
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Cohort Studies
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Extensively Drug-Resistant Tuberculosis / diagnosis
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Extensively Drug-Resistant Tuberculosis / drug therapy*
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Fluoroquinolones / therapeutic use*
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Humans
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Prognosis
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Streptomycin / therapeutic use*
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Treatment Outcome
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Tuberculosis, Multidrug-Resistant / diagnosis
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Tuberculosis, Multidrug-Resistant / drug therapy*
Substances
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Antitubercular Agents
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Fluoroquinolones
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Streptomycin