Screening of food raw materials for the presence of Shiga toxin-producing Escherichia coli O91:H21

Lett Appl Microbiol. 2009 Apr;48(4):447-51. doi: 10.1111/j.1472-765X.2008.02549.x. Epub 2009 Feb 2.

Abstract

Aims: To provide information on the prevalence and detection, in foods, of Shiga toxin-producing Escherichia coli (STEC) O91:H21.

Methods and results: Seven hundred fifteen minced beef meats and 205 raw milk samples were analysed by stx-specific PCR-ELISA. Samples positive for stx were subsequently tested for the presence of wzy-O91, fliC-H21 and the adhesin-encoding gene saa. For minced meat, 16 (2.2%) and 11 (1.5%) samples were found positive for (stx, wzy-O91, fliC-H21) and (stx, wzy-O91, fliC-H21, saa) combinations, respectively. For raw milk, seven (3.4%) samples were found positive for the (stx, wzy-O91, fliC-H21) combination but none of these contained saa. Two STEC O91:H21 saa-positive strains and three STEC O91 H21- and saa-negative strains were isolated by colony hybridization.

Conclusions: A low prevalence of potentially pathogenic STEC O91:H21 in food products was found using a combination of PCR assays targeting stx, wzy-O91, fliC-H21 and saa.

Significance and impact of the study: The PCR-based approach described here represents a valuable method for rapid screening of food samples contaminated by STEC O91:H21.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adhesins, Bacterial / genetics
  • Animals
  • Cattle
  • Enzyme-Linked Immunosorbent Assay
  • Escherichia coli Proteins / genetics
  • Flagellin
  • Food Contamination / analysis*
  • Humans
  • Meat Products / microbiology*
  • Milk / microbiology*
  • Polymerase Chain Reaction / methods
  • Prevalence
  • Shiga Toxin / biosynthesis*
  • Shiga Toxin / genetics
  • Shiga-Toxigenic Escherichia coli / genetics
  • Shiga-Toxigenic Escherichia coli / isolation & purification*

Substances

  • Adhesins, Bacterial
  • Escherichia coli Proteins
  • FliC protein, E coli
  • SAA protein, E coli
  • Flagellin
  • Shiga Toxin