Indolynes as electrophilic indole surrogates: fundamental reactivity and synthetic applications

Sarah M Bronner; Kevin B Bahnck; Neil K Garg

doi:10.1021/ol802958a

Indolynes as electrophilic indole surrogates: fundamental reactivity and synthetic applications

Org Lett. 2009 Feb 19;11(4):1007-10. doi: 10.1021/ol802958a.

Authors

Sarah M Bronner¹, Kevin B Bahnck, Neil K Garg

Affiliation

¹ Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095-1569, USA.

PMID: 19178159
DOI: 10.1021/ol802958a

Abstract

A mild method to access a variety of substituted indole derivatives has been developed. The strategy relies on the generation of highly reactive indolyne intermediates, which function as electrophilic indole surrogates.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Catalysis
Combinatorial Chemistry Techniques*
Indoles / chemical synthesis*
Indoles / chemistry*
Models, Molecular
Molecular Structure

Substances

Indoles