Biomarkers for nononcologic gastrointestinal diseases

Immunol Allergy Clin North Am. 2009 Feb;29(1):119-27, xi. doi: 10.1016/j.iac.2008.09.012.

Abstract

Biomarkers are objectively measured indicators of normal and abnormal biologic processes and may vary with therapeutic interventions. In the area of gastrointestinal diseases, biomarker research is primarily in the area of cancer biology. Little is known about biomarkers in connection with other gastrointestinal disorders. This article reviews biomarker data for nononcologic gastrointestinal processes with a focus on allergic disorders.

Publication types

  • Review

MeSH terms

  • Biomarkers*
  • Chemokine CCL26
  • Chemokines, CC / blood
  • Chemokines, CC / immunology
  • Eosinophils / immunology
  • Eosinophils / metabolism*
  • Eosinophils / pathology
  • Food Hypersensitivity / blood
  • Food Hypersensitivity / complications
  • Food Hypersensitivity / immunology
  • Gastrointestinal Diseases / blood
  • Gastrointestinal Diseases / complications
  • Gastrointestinal Diseases / diagnosis
  • Gastrointestinal Diseases / immunology*
  • Humans
  • Immunoglobulin E / blood
  • Interleukin-13 / blood
  • Interleukin-13 / immunology
  • Interleukin-2 Receptor alpha Subunit / immunology
  • Interleukin-2 Receptor alpha Subunit / metabolism
  • Mast Cells / immunology
  • Mast Cells / metabolism*
  • Mast Cells / pathology
  • Matrix Metalloproteinase 9 / immunology
  • Matrix Metalloproteinase 9 / urine
  • T-Lymphocyte Subsets / immunology
  • T-Lymphocyte Subsets / metabolism*
  • T-Lymphocyte Subsets / pathology
  • T-Lymphocytes, Regulatory / immunology
  • T-Lymphocytes, Regulatory / metabolism*
  • T-Lymphocytes, Regulatory / pathology
  • Transforming Growth Factor beta / immunology
  • Transforming Growth Factor beta / metabolism
  • Vascular Endothelial Growth Factor A / blood
  • Vascular Endothelial Growth Factor A / immunology

Substances

  • Biomarkers
  • CCL26 protein, human
  • Chemokine CCL26
  • Chemokines, CC
  • Interleukin-13
  • Interleukin-2 Receptor alpha Subunit
  • Transforming Growth Factor beta
  • Vascular Endothelial Growth Factor A
  • Immunoglobulin E
  • Matrix Metalloproteinase 9