Abstract
A 47-year-old man who was diagnosed as Crohn's disease at the age of 27 became aware of a mass on the forehead. CT and PET scan revealed many scattered tumors in his body. The CEA level was 4424 ng/ml. Primary lesion was not detected by the surveillance of whole gastro-intestinal tract. Liver tumor biopsy samples were histologicaly analyzed and were diagnosed as adenocarcinoma. Further immunohistochemical analysis revealed that the biopsy material had colonic character determined by positive CK20 and negative CK7 staining. Therefore, we performed 12 cycles of mFOLFOX6 chemotherapy. It was effective with the reduced size of tumors and the decreased level of CEA.
Publication types
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Case Reports
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English Abstract
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Review
MeSH terms
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Adenocarcinoma / diagnosis
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Adenocarcinoma / drug therapy*
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Adenocarcinoma / etiology
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Antineoplastic Combined Chemotherapy Protocols / administration & dosage
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Crohn Disease / complications*
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Fluorouracil / administration & dosage
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Humans
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Leucovorin / administration & dosage
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Male
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Middle Aged
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Neoplasms, Multiple Primary / diagnosis
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Neoplasms, Multiple Primary / drug therapy*
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Neoplasms, Multiple Primary / etiology
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Neoplasms, Unknown Primary / diagnosis
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Neoplasms, Unknown Primary / drug therapy*
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Neoplasms, Unknown Primary / etiology
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Organoplatinum Compounds / administration & dosage
Substances
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Organoplatinum Compounds
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Leucovorin
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Fluorouracil