Engineered marine Antarctic bacterium Pseudoalteromonas haloplanktis TAC125: a promising micro-organism for the bioremediation of aromatic compounds

J Appl Microbiol. 2009 Jan;106(1):49-56. doi: 10.1111/j.1365-2672.2008.03971.x. Epub 2008 Dec 11.

Abstract

Aims: The recombinant Antarctic Pseudoalteromonas haloplanktis TAC125 (P. haloplanktis TAC/tou) expressing toluene-o-xylene monooxygenase (ToMO) can efficiently convert several aromatic compounds into their corresponding catechols in a broad range of temperature. When the genome of P. haloplanktis TAC125 was analysed in silico, the presence of a DNA sequence coding for a putative laccase-like protein was revealed. It is well known that bacterial laccases are able to oxidize dioxygenated aromatic compounds such as catechols.

Methods and results: We analysed the catabolic features, conferred by recombinant ToMO activity and the endogenous laccase enzymatic activity, of P. haloplanktis TAC/tou engineered strain and its ability to grow on aromatic compounds as sole carbon and energy sources.

Conclusions: Results presented highlight the broad potentiality of P. haloplanktis TAC/tou cells expressing recombinant ToMO in bioremediation and suggest the use of this engineered Antarctic bacterium in the bioremediation of chemically contaminated marine environments and/or cold effluents.

Significance and impact of the study: This paper demonstrates the possibility to confer new and specific degradative capabilities to a bacterium isolated from an unpolluted environment (Antarctic seawater) transforming it into a bacterium able to grow on phenol as sole carbon and energy source.

MeSH terms

  • Antarctic Regions
  • Biodegradation, Environmental
  • Catechols / metabolism
  • Copper / metabolism
  • Gene Expression Regulation
  • Laccase / analysis*
  • Laccase / genetics
  • Oxygenases
  • Phenol / metabolism*
  • Pseudoalteromonas / enzymology*
  • Pseudoalteromonas / genetics
  • Pseudoalteromonas / growth & development
  • RNA, Bacterial / genetics
  • Reverse Transcriptase Polymerase Chain Reaction
  • Temperature

Substances

  • Catechols
  • RNA, Bacterial
  • Phenol
  • Copper
  • Laccase
  • Oxygenases
  • toluene 2-xylene monooxygenase
  • catechol