Models use leptin and calculus to count calories

Kevin D Hall; Steven B Heymsfield

doi:10.1016/j.cmet.2008.12.006

Models use leptin and calculus to count calories

Cell Metab. 2009 Jan 7;9(1):3-4. doi: 10.1016/j.cmet.2008.12.006.

Authors

Kevin D Hall¹, Steven B Heymsfield

Affiliation

¹ Laboratory of Biological Modeling, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-5621, USA.

PMID: 19117539
DOI: 10.1016/j.cmet.2008.12.006

Abstract

Thermostats have "set-points" that engineers design with mathematical rigor. Work in this issue of Cell Metabolism (Tam et al., 2009) applies similar modeling strategies to explore the control of murine energy and body weight homeostasis by leptin.

Publication types

Comment

MeSH terms

Algorithms
Animals
Body Weight*
Energy Metabolism
Leptin / metabolism*
Mice
Models, Biological*
Obesity / metabolism

Substances

Leptin