We study the spatial correlation of a two-photon entangled state produced in a multistripe periodically poled LiTaO3 crystal by spontaneous parametric down-conversion. The far-field diffraction-interference experiments reveal that the transverse modulation of domain patterns transforms the spatial mode function of the two-photon state. This result offers an approach to prepare a novel type of two-photon state with a unique spatial entanglement by using a domain-engineering technique.