Peripheral ulcerative keratitis after trabeculectomy in a patient with rheumatoid arthritis

Cornea. 2009 Jan;28(1):111-3. doi: 10.1097/ICO.0b013e318182fc01.

Abstract

Purpose: To report the unusual occurrence of peripheral ulcerative keratitis, 10 days after trabeculectomy in a 35-year-old patient with rheumatoid arthritis (RA).

Methods: Observational case report.

Results: A 35-year-old patient with RA and secondary Sjögren disease underwent an uneventful fornix-based trabeculectomy. Ten days after surgery, slit-lamp examination revealed a peripheral corneal ulcer extending from 5- to 7-o'clock positions with a surrounding inflammatory infiltrate and adjacent conjunctival injection. The ulcer was treated with systemic and topical steroids, antibiotic eyedrops, artificial tears, and a bandage soft contact lens. Since then, corneal re-epithelialization started and the patient's symptoms subsided. The ulcer improved steadily within 2 months while the patient used a soft contact lens. The ulcer did not reoccur in the 18 months follow-up while the patient remained under systemic treatment.

Conclusion: This report highlights the importance of careful examination and close postoperative follow-up in patients with RA undergoing any intraocular surgery, to diagnose a possible development of peripheral ulcerative keratitis. Although the incidence is rare, prompt diagnosis of the peripheral ulceration is essential because if untreated it may seriously affect patient's vision.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use
  • Arthritis, Rheumatoid / complications*
  • Contact Lenses, Hydrophilic
  • Corneal Ulcer / etiology*
  • Corneal Ulcer / therapy
  • Female
  • Glaucoma / surgery*
  • Humans
  • Keratitis / etiology*
  • Keratitis / therapy
  • Ophthalmic Solutions / therapeutic use
  • Postoperative Complications*
  • Sjogren's Syndrome / complications
  • Steroids / administration & dosage
  • Steroids / therapeutic use
  • Time Factors
  • Trabeculectomy*

Substances

  • Anti-Bacterial Agents
  • Ophthalmic Solutions
  • Steroids