Objective: To investigate the clinical value of CT guided radioactive seed (125)I implantation in treating bone metastasis.
Methods: 28 multiple bone metastatic tumor patients with 116 metastatic lesions totally, adenocarcinoma of lung in 6 cases, squamous cell carcinoma of lung, renal clear-cell carcinoma, and carcinoma of prostate in 4 cases each, hepatocellular carcinoma and colon carcinoma in 3 cases each, breast carcinoma in 2 cases, and malignant schwannoma and pancreatic cancer in 1 case each, 13 males and 15 females, aged 49.8, underwent CT guided radioactive seed (125)I implantation into bone metastatic lesions.
Results: In these 28 cases, complete pain relief (CR) was observed in 16 cases, partial relief (PR) in 7 cases, and no change (NC) in 5 cases with an effective rate of 82.1%. Among the 116 lesions in these 28 cases local control (LC) was seen in 93 cases, NC in 17, and PD in 6. The response rate was 80.2%.
Conclusion: CT guided radioactive seed (125)I implantation procedure has good clinical effects in treating bone metastasis with minimal invasive and few complications.