Update on infectious diseases in pediatric solid organ transplantation

Curr Opin Organ Transplant. 2008 Oct;13(5):500-5. doi: 10.1097/MOT.0b013e328310b0a4.

Abstract

Purpose of review: Numerous recent advances have been made in the field of infectious diseases and pediatric solid organ transplant.

Recent findings: Although many studies contain somewhat small cohorts of individuals, when summarized together they contribute significantly to our knowledge about pediatric solid organ transplant, especially regarding risk factors for infection, management of BK virus nephropathy, the use of live viral vaccines, and consideration for rare infections as well as donor-derived infections.

Summary: In sum, these recent advances in infection in the field of pediatric solid organ transplant will help decrease infection, thus improving morbidity and mortality, as well as transplant outcomes, especially by decreasing direct (graft injury) and indirect (immune upregulation) effects on organ transplantation. This review will focus on recent advances in the field of infectious diseases in pediatric solid organ transplant by highlighting some of the most important and interesting articles in the field within the past few years.

Publication types

  • Review

MeSH terms

  • Anti-Infective Agents / therapeutic use*
  • Bacterial Vaccines
  • Child
  • Child, Preschool
  • Communicable Diseases / etiology*
  • Communicable Diseases / microbiology
  • Communicable Diseases / parasitology
  • Communicable Diseases / virology
  • Fungal Vaccines
  • Humans
  • Incidence
  • Infant
  • Infection Control*
  • Organ Transplantation / adverse effects*
  • Protozoan Vaccines
  • Risk Factors
  • Vaccination*

Substances

  • Anti-Infective Agents
  • Bacterial Vaccines
  • Fungal Vaccines
  • Protozoan Vaccines