Sleep apnea in patients with heart failure: could cardiac resynchronization therapy be the first line treatment?

Int J Cardiol. 2010 Apr 1;140(1):128-30; author reply 130-1. doi: 10.1016/j.ijcard.2008.11.027. Epub 2008 Nov 28.

Abstract

Adaptive servo-ventilation as well as continuous and bi-level positive airway pressure seems to effectively treat sleep apnea syndrome (SAS) in patients with chronic heart failure (CHF), and to improve left ventricular function. However, no randomized data show a significant impact of ventilation on survival in patients with CHF. By contrast, there is overwhelming evidence that cardiac resynchronization therapy (CRT) improves outcomes in patients with CHF. CRT also provides a clinically significant decrease in SAS severity in patients with CHF. Consequently, CRT eligibility criteria should always be searched for in patients with severe CHF having SAS.

Publication types

  • Comment
  • Letter

MeSH terms

  • Cardiac Pacing, Artificial*
  • Heart Failure / epidemiology*
  • Heart Failure / physiopathology
  • Heart Failure / therapy*
  • Humans
  • Respiration, Artificial / methods*
  • Sleep Apnea Syndromes / epidemiology*
  • Sleep Apnea Syndromes / physiopathology
  • Sleep Apnea, Central / epidemiology
  • Sleep Apnea, Central / physiopathology
  • Sleep Apnea, Central / therapy
  • Treatment Outcome
  • Ventricular Function, Left