N-Arylation of amines, amides, imides and sulfonamides with arylboroxines catalyzed by simple copper salt/EtOH system

Beilstein J Org Chem. 2008:4:40. doi: 10.3762/bjoc.4.40. Epub 2008 Nov 7.

Abstract

The coupling of arylboroxines with a variety of amines, amides, imides and sulfonamides catalyzed by a copper salt/EtOH system has been developed. In the absence of a base or additive the corresponding N-arylation products were obtained in moderate to excellent yields.

Keywords: N-arylation; arylboroxine; copper salt; cross-coupling; ethanol.