JAK2V617F mutational status and allele burden have little influence on clinical phenotype and prognosis in patients with post-polycythemia vera and post-essential thrombocythemia myelofibrosis

Haematologica. 2009 Jan;94(1):144-6. doi: 10.3324/haematol.13721. Epub 2008 Nov 27.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Alleles*
  • Female
  • Humans
  • Janus Kinase 2 / genetics
  • Janus Kinase 2 / metabolism*
  • Male
  • Middle Aged
  • Mutation / genetics
  • Phenotype
  • Polycythemia Vera / enzymology*
  • Polycythemia Vera / genetics
  • Polycythemia Vera / pathology*
  • Prognosis
  • Thrombocythemia, Essential / enzymology*
  • Thrombocythemia, Essential / genetics
  • Thrombocythemia, Essential / pathology*
  • Valine / genetics
  • Valine / metabolism

Substances

  • JAK2 protein, human
  • Janus Kinase 2
  • Valine