Breast carcinoma metastatic to the orbit: an unusually late presentation

Ophthalmic Plast Reconstr Surg. 2008 Nov-Dec;24(6):480-2. doi: 10.1097/IOP.0b013e31818b6adc.

Abstract

An 83-year-old woman, diagnosed with breast carcinoma 28 years earlier, presented with left hyperglobus and limitation of extraocular motility. CT and MRI showed bilateral nodular thickening of extraocular muscles. Left orbital biopsy disclosed metastatic breast carcinoma. Subsequent positron-emission tomography/CT revealed diffuse metastatic disease. To the authors' knowledge, this case represents the longest reported interval from the diagnosis of primary breast cancer to the presentation of orbital metastasis.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged, 80 and over
  • Antineoplastic Agents / therapeutic use
  • Breast Neoplasms / pathology*
  • Breast Neoplasms / surgery
  • Carcinoma / diagnosis
  • Carcinoma / secondary*
  • Carcinoma / therapy
  • Diagnosis, Differential
  • Female
  • Follow-Up Studies
  • Humans
  • Letrozole
  • Magnetic Resonance Imaging
  • Mastectomy, Radical / methods
  • Nitriles / therapeutic use
  • Orbital Neoplasms / diagnosis
  • Orbital Neoplasms / drug therapy
  • Orbital Neoplasms / secondary*
  • Tomography, Emission-Computed, Single-Photon
  • Tomography, X-Ray Computed
  • Triazoles / therapeutic use

Substances

  • Antineoplastic Agents
  • Nitriles
  • Triazoles
  • Letrozole