In-vitro expression of adhesion molecules and bone specific markers are depending on the cell culture material

N Salin; A K Ishak; S Abdul Rahman; M Ali; H Mohamad Nawawi; M S Mohamed Said; G A Froemming

In-vitro expression of adhesion molecules and bone specific markers are depending on the cell culture material

Med J Malaysia. 2008 Jul:63 Suppl A:67-8.

Authors

N Salin¹, A K Ishak, S Abdul Rahman, M Ali, H Mohamad Nawawi, M S Mohamed Said, G A Froemming

Affiliation

¹ Institute of Medical Molecular Biotechnology (IMMB), Faculty of Medicine, Universiti Teknologi MARA.

PMID: 19024987

Abstract

Bone formation is an active process whereby osteoblasts are found on the surface of the newly formed bone. Adhesion to extracellular matrix is essential for the development of bone however not all surfaces are suitable for osteoblast adhesion and don't support osteoblastic functions. The objective of this study was to test the suitability of a collagen based microcarrier which would support osteoblastic functions.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biomarkers*
Bone and Bones / physiology*
Cell Adhesion Molecules / physiology*
Cell Culture Techniques*
Cell Survival
Collagen*
Extracellular Matrix / physiology*
Humans
Immunophenotyping
Osteoblasts*
Osteogenesis / physiology*

Substances

Biomarkers
Cell Adhesion Molecules
Collagen