[Cognitive functions after surgery and stenting for extracranial stenosis of the carotid artery]

Nervenarzt. 2008 Dec;79(12):1424, 1426-8, 1430-1. doi: 10.1007/s00115-008-2600-5.
[Article in German]

Abstract

Background: This prospective, controlled, randomised study evaluates differences concerning cognitive functions between carotid endarterectomy (CEA) and stent-protected angioplasty (CAS) as a treatment for symptomatic carotid stenosis. Both techniques include risks whose effect on neuropsychological abilities remains yet unknown.

Methods: Twenty-seven patients suffering from high-grade symptomatic carotid stenosis underwent neuropsychological testing before, 1 month, and 6 months after treatment. After the first testing patients were randomly assigned for CEA (n=10) or CAS (n=17) as treatment. The patients' cognitive functions were compared to those of 13 healthy controls.

Results: Whether patients underwent CEA or CAS made no difference in the neuropsychological outcome 4 weeks and 6 months after treatment. Patients always performed worse than the healthy controls.

Conclusion: Both techniques seem to have no different effect on cognitive functions.

Publication types

  • Comparative Study
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Aged, 80 and over
  • Angioplasty, Balloon*
  • Carotid Artery, Internal*
  • Carotid Stenosis / complications
  • Carotid Stenosis / therapy*
  • Cognition Disorders / diagnosis
  • Cognition Disorders / therapy*
  • Endarterectomy, Carotid*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neuropsychological Tests / statistics & numerical data*
  • Postoperative Complications / diagnosis
  • Prospective Studies
  • Psychometrics
  • Stents*