Look beyond the hERG mutation: a neutral SCN5A variant may turn lidocaine into a threat

Heart Rhythm. 2008 Nov;5(11):1575-6. doi: 10.1016/j.hrthm.2008.09.006. Epub 2008 Sep 6.
No abstract available

Publication types

  • Editorial
  • Comment

MeSH terms

  • Atrioventricular Block / genetics*
  • ERG1 Potassium Channel
  • Ether-A-Go-Go Potassium Channels / genetics*
  • Humans
  • Long QT Syndrome / genetics*
  • Muscle Proteins / genetics*
  • Mutation
  • NAV1.5 Voltage-Gated Sodium Channel
  • Phenotype
  • Sodium Channels / genetics*
  • Tachycardia, Ventricular / genetics*

Substances

  • ERG1 Potassium Channel
  • Ether-A-Go-Go Potassium Channels
  • KCNH2 protein, human
  • Muscle Proteins
  • NAV1.5 Voltage-Gated Sodium Channel
  • SCN5A protein, human
  • Sodium Channels