Addressing the PEG mucoadhesivity paradox to engineer nanoparticles that "slip" through the human mucus barrier
Angew Chem Int Ed Engl
.
2008;47(50):9726-9.
doi: 10.1002/anie.200803526.
Authors
Ying-Ying Wang
1
,
Samuel K Lai
,
Jung Soo Suk
,
Amanda Pace
,
Richard Cone
,
Justin Hanes
Affiliation
1
Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
PMID:
18979480
PMCID:
PMC2666733
DOI:
10.1002/anie.200803526
No abstract available
Publication types
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
MeSH terms
Chemical Engineering
Humans
Molecular Weight
Mucus / metabolism*
Nanoparticles / chemistry*
Polyethylene Glycols / chemistry*
Substances
Polyethylene Glycols
Grants and funding
R01EB003558/EB/NIBIB NIH HHS/United States
R21HL089816/HL/NHLBI NIH HHS/United States
U01 AI066726/AI/NIAID NIH HHS/United States
R01 EB003558/EB/NIBIB NIH HHS/United States
R01 EB003558-02/EB/NIBIB NIH HHS/United States
R21 HL089816-01A1/HL/NHLBI NIH HHS/United States
R21 HL089816/HL/NHLBI NIH HHS/United States
5U01AI066726/AI/NIAID NIH HHS/United States