Abstract
To determine links between human rhinoviruses (HRV) and asthma, we used data from a case-control study, March 2003-February 2004, among children with asthma. Molecular characterization identified several likely new HRVs and showed that association with asthma exacerbations was largely driven by HRV-A and a phylogenetically distinct clade of 8 strains, genogroup C.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adolescent
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Asthma / epidemiology
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Asthma / pathology*
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Asthma / virology*
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Case-Control Studies
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Child
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Child, Preschool
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Disease Progression
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Georgia
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Humans
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Phylogeny
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Picornaviridae Infections / complications*
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Rhinovirus / classification*
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Rhinovirus / genetics
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Rhinovirus / isolation & purification
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Urban Population
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Viral Proteins / genetics
Substances
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Viral Proteins
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viral protein 1, rhinovirus