Hg2+ selective fluorescent and colorimetric sensor: its crystal structure and application to bioimaging

Org Lett. 2008 Nov 20;10(22):5235-8. doi: 10.1021/ol8022598. Epub 2008 Oct 28.

Abstract

A Hg(2+)-selective rhodamine 6G derivative bearing thiolactone moiety was synthesized, and its crystal structure with Hg(2+) is presented to explain the binding mode. In addition, highly selective "off-on"-type fluorescent change upon the addition of Hg(2+) was also applied to bioimaging.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Caenorhabditis elegans / chemistry
  • Colorimetry
  • Crystallography, X-Ray
  • Fluorescent Dyes / chemical synthesis
  • Fluorescent Dyes / chemistry*
  • Lactones / chemistry
  • Mercury / analysis*
  • Rhodamines / chemical synthesis
  • Rhodamines / chemistry*
  • Sensitivity and Specificity
  • Spectrometry, Fluorescence

Substances

  • Fluorescent Dyes
  • Lactones
  • Rhodamines
  • rhodamine 6G
  • Mercury