[Acute heart failure and preserved systolic function: can we explain all only by the diastolic dysfunction? A prospective study on 145 patients hospitalized for acute pulmonary edema]

Arch Mal Coeur Vaiss. 2006 Dec;99(12):1178-83.
[Article in French]

Abstract

Introduction: Heart failure with conserved systolic function is frequent and attributed to the diastolic dysfunction. The diagnosis of diastolic heart failure requires the association of clinical signs of heart failure, a conserved left ventricular systolic function and a diastolic dysfunction.

Objective: To determine the proportion of cases of isolated diastolic heart failure among patients hospitalized for acute pulmonary edema.

Methods: The left ventricular ejection fraction (LVEF), the diastolic function and levels of NT-proBNP have been assessed at admission of 145 patients hospitalized for acute pulmonary edema.

Results: 49% of patients included were older than 80 years (mean age 78.6 + 0.9 years). Among the 83 patients with conserved LVEF, 25% had an ischemic heart disease, 24% a severe valvular disease, 22% an atrial fibrillation, 5% a severe bradycardia, 2% a severe hypertrophic obstructive cardiomyopathy. Only 15 patients presented an isolated diastolic heart failure. The level of NT-proBNP was correlated to LVEF but was not able to identify those with isolated diastolic heart failure in the group with "conserved systolic function".

Conclusion: Among patients hospitalized for acute pulmonary edema, the prevalence of heart failure with conserved systolic function is high, but only 10% of them presented an isolated diastolic heart failure. The NT-proBNP levels do not permit to identify them.

Publication types

  • English Abstract

MeSH terms

  • Acute Disease
  • Aged
  • Aged, 80 and over
  • Diastole / physiology*
  • Heart Failure / etiology
  • Heart Failure / physiopathology*
  • Heart Ventricles / physiopathology
  • Hemodynamics
  • Humans
  • Myocardial Ischemia / complications
  • Prospective Studies
  • Pulmonary Artery / physiopathology
  • Pulmonary Edema / complications*
  • Pulmonary Edema / physiopathology
  • Pulmonary Veins / physiopathology
  • Reference Values
  • Systole / physiology*