Abstract
In this study, we report the DNA sequence and biological analysis of a mycobacterial mercury resistance operon encoding a novel Hg(2+) transporter. MerH was found to transport mercuric ions in Escherichia coli via a pair of essential cysteine residues but only when coexpressed with the mercuric reductase.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Bacterial Proteins / metabolism*
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Cation Transport Proteins / genetics*
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Cation Transport Proteins / metabolism*
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Conserved Sequence
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DNA Primers
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Drug Resistance, Microbial / genetics*
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Escherichia coli / genetics
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Mercury Compounds / metabolism*
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Mercury Compounds / pharmacology*
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Molecular Sequence Data
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Mycobacterium marinum / drug effects*
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Mycobacterium marinum / genetics*
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Operon / genetics*
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Plasmids
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Sequence Alignment
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Sequence Homology, Amino Acid
Substances
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Bacterial Proteins
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Cation Transport Proteins
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DNA Primers
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Mercury Compounds