Subcutaneous fistulae in a patient with femoral hypoplasia due to Actinomyces europaeus and Actinomyces turicensis

Infection. 2009 Jun;37(3):289-91. doi: 10.1007/s15010-008-7392-9. Epub 2008 Oct 14.

Abstract

Infections due to Actinomyces europaeus or Actinomyces turicensis have only rarely been reported. We describe a case of chronic fistulae caused by a coinfection with A. europaeus and A. turicensis in an immunocompetent male patient with a severe congenital femur hypoplasia. Actinomycosis is most probably the consequence of a postoperative wound infection after a prior surgical intervention. Both Actinomyces species were identified by 16S rRNA gene sequencing. The Actinomyces-caused fistulae were treated by excision and a 1-week course of i.v. vancomycin followed by a 1-week course of p.o. cefuroxime.

Publication types

  • Case Reports

MeSH terms

  • Actinomyces / classification
  • Actinomyces / isolation & purification*
  • Actinomycosis / complications*
  • Actinomycosis / drug therapy
  • Actinomycosis / surgery
  • Antifungal Agents / therapeutic use
  • Cefuroxime / therapeutic use
  • Femur / abnormalities*
  • Fistula / etiology*
  • Fistula / microbiology
  • Fistula / therapy
  • Humans
  • Immunocompetence
  • Knee Joint* / microbiology
  • Lower Extremity Deformities, Congenital / complications
  • Lower Extremity Deformities, Congenital / surgery
  • Male
  • RNA, Bacterial / analysis
  • RNA, Ribosomal, 16S / analysis
  • Soft Tissue Infections / complications*
  • Soft Tissue Infections / drug therapy
  • Surgical Wound Infection / complications*
  • Vancomycin / therapeutic use
  • Young Adult

Substances

  • Antifungal Agents
  • RNA, Bacterial
  • RNA, Ribosomal, 16S
  • Vancomycin
  • Cefuroxime