Abstract
Infections due to Actinomyces europaeus or Actinomyces turicensis have only rarely been reported. We describe a case of chronic fistulae caused by a coinfection with A. europaeus and A. turicensis in an immunocompetent male patient with a severe congenital femur hypoplasia. Actinomycosis is most probably the consequence of a postoperative wound infection after a prior surgical intervention. Both Actinomyces species were identified by 16S rRNA gene sequencing. The Actinomyces-caused fistulae were treated by excision and a 1-week course of i.v. vancomycin followed by a 1-week course of p.o. cefuroxime.
MeSH terms
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Actinomyces / classification
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Actinomyces / isolation & purification*
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Actinomycosis / complications*
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Actinomycosis / drug therapy
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Actinomycosis / surgery
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Antifungal Agents / therapeutic use
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Cefuroxime / therapeutic use
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Femur / abnormalities*
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Fistula / etiology*
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Fistula / microbiology
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Fistula / therapy
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Humans
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Immunocompetence
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Knee Joint* / microbiology
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Lower Extremity Deformities, Congenital / complications
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Lower Extremity Deformities, Congenital / surgery
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Male
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RNA, Bacterial / analysis
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RNA, Ribosomal, 16S / analysis
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Soft Tissue Infections / complications*
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Soft Tissue Infections / drug therapy
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Surgical Wound Infection / complications*
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Vancomycin / therapeutic use
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Young Adult
Substances
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Antifungal Agents
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RNA, Bacterial
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RNA, Ribosomal, 16S
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Vancomycin
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Cefuroxime