Abstract
A bone marrow transplant recipient with disseminated trichosporonosis was successfully treated with voriconazole. Quantitative PCR assay results for Trichosporon asahii DNA in the sera were well correlated with the patient's clinical course. Based on the in vitro susceptibility test, the organism was susceptible to voriconazole.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Antifungal Agents / pharmacology
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Antifungal Agents / therapeutic use
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Antigens, Fungal / blood
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Bone Marrow Transplantation
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DNA, Fungal / blood*
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Graft vs Host Disease / complications
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Humans
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Immunocompromised Host
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Latex Fixation Tests
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Male
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Microbial Sensitivity Tests
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Mycoses / blood
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Mycoses / diagnosis*
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Mycoses / drug therapy
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Mycoses / microbiology
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Polymerase Chain Reaction*
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Polysaccharides / blood
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Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications
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Pyrimidines / therapeutic use
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Triazoles / therapeutic use
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Trichosporon / drug effects
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Trichosporon / genetics
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Trichosporon / isolation & purification*
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Voriconazole
Substances
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Antifungal Agents
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Antigens, Fungal
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DNA, Fungal
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Polysaccharides
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Pyrimidines
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Triazoles
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glucuronoxylomannan
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Voriconazole