High genetic diversity of nontypeable Haemophilus influenzae isolates from two children attending a day care center

J Clin Microbiol. 2008 Nov;46(11):3817-21. doi: 10.1128/JCM.00940-08. Epub 2008 Sep 24.

Abstract

Twenty-one nontypeable Haemophilus influenzae (NTHi) isolates from the throats of two healthy children were genotyped by multilocus sequence typing. Nine unique sequence types (STs) were identified. These STs were scattered throughout the phylogenetic tree of reported NTHi STs, demonstrating the high level of NTHi diversity found in colonized children.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural

MeSH terms

  • Bacterial Typing Techniques
  • Child
  • Child Day Care Centers
  • Cluster Analysis
  • DNA Fingerprinting
  • DNA, Bacterial / genetics
  • Genotype
  • Haemophilus Infections / microbiology*
  • Haemophilus influenzae / classification*
  • Haemophilus influenzae / genetics*
  • Haemophilus influenzae / isolation & purification
  • Humans
  • Pharynx / microbiology
  • Phylogeny
  • Polymorphism, Genetic*
  • Sequence Analysis, DNA

Substances

  • DNA, Bacterial